Common Side Effects Some people may experience mild side effects from vitamin B12 injections, including pain or redness at the injection site, mild diarrhea, or itching
Insert the needle at a 90-degree angle into the muscle
Prior B12 values show whether the elevation is persistent or already on its way down, and any CBC, liver tests, or renal function already on file may point to a cause before anything new is ordered
The Neelakantan 2018 paper showed strong oral absorption in cell uptake (Caco-2) assays, which is why most research community use is by mouth instead of by injection
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For vitamin B deficiency (e.g., pernicious anemia), a common regimen is to begin with frequent intramuscular injections to replenish body stores